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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52f0def2db4a9802e49ddb2dfd7f8f872263c1d9bb589d41211229f175256f4c' 
  AND token = '3r7gXPpUpO5wgug586nJZp4B9kB8f/LSX/Nx4+6AV7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}