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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8fddef13bde64d7a2038f079ce085510afc993ca7d7c2be7e92fa2683f47426' 
  AND token = '+6q11dKTeIU3uLdWcrCRBHw9TtX57jVbpNbzecvDiR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}