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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dbfe0e163dfb2fb8917e798610138afcc93ade0b064be5977071437d7059f0b' 
  AND token = 'laQ9Ruqy0zsP4SYxg4BHbDR53SKyK8Ci8FY/HHzY0tw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}