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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c1891bf70995565305238b28fc5086b3b82d9db389bd15ed95c4f8178d6f4c5' 
  AND token = '25xUH4qU/u9EhtJlrCUh0AmDyiJN8wMP0lr79DjysEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}