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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e0f0470fbcd6c4d599572a6dc7b6eae9764cf9b2690029d1c4c5e96fb9f6333' 
  AND token = '43eLjs8ud4hXzZ8CIuxfbIr/3lo7UtfjLPhkmR98L8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}