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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ea5a0325eb2c61afa9e5fb541d424941aa86e278ef1a79efd4326a047b24018' 
  AND token = '54mgcIClyx9CVYR/Z6FFmF36f3XWGJZywNkDEfbzskA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}