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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c360eea0b30ad87c56acbf8d1ef6b703999f97f1140c58c5a511865f3b20d79c' 
  AND token = 'Jz6EqT6+Kr6kp5P6PdqtFtKBM3++bsHjSZCfKuarCks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}