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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9a25ddece5f37e80495f865bc65826cdd88b2639422322017ef243a7b494282' 
  AND token = 'onUyAhbtFMjA370a1DYDYK+OWKFMTD3OhP7f3hy4Lec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}