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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fc1563eaed7a2366aa4f02ed9895d2a2b6d1056f815b970acab3997c3ebad96' 
  AND token = 'O1EPLOhK6Qh/WAGcwnq4Tjwz3j8418sGyg6JIPODErU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}