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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f01aff4022747870426df3e46fb05f27968e8611a51e886cc2954ade1bc3dd9b' 
  AND token = 'Jnmf/KI44yWh1Aa55aFRwhZby9+XPrFq+w27psfx5V0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}