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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0808c04bdb7c0db9c68d5b6c53eebf74f02caa752ca149ddbf59e64efa86f67f' 
  AND token = 'lEah3LQHyhvkh9D2cvYO9y4FjIfCbkPAp/EFdxgnht0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}