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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d83a0ed1e13d043c42f21c7ab9441ee1dd758f2b6d8d549213fa27e27d7dad1' 
  AND token = 'OtFsWCTjG1TYLpU3swk/Nvd6DsCgjb2P4JrrK3UuyZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}