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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ae4b0325b4105c89a9117ab6baaf8cb7fdf686f8b90c016923479076bd49524' 
  AND token = '3atoSWCrWeok3Lw5RvDy+LylqR5B2mKKHEHuEwqs8ok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}