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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b749c3b24b70360d15cb28c8bb0d98af4e474f80fb8cc69b2e62f1988d92480' 
  AND token = 'dHN6yjE+1mpXrM+V+pLmP6mfmnzcLAxZPJVwzkM11I4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}