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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2ce401426432eb64b3d9f33d42d2867968205ed025defc7d47f4b016cd2877a' 
  AND token = 'wxfEFXr5S/XqV5duhKvZGua2T2hlifaThiuNSJtPWSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}