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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cf49400011c0684519a85ce88f87d37ce10969f7666150e5ea274e396a80eab' 
  AND token = 'cSn/BYe3SkfRGXtbOHJ0coYCHdWOyHYiH5J6OQVbe/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}