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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19591a2cda16a41c181fb7e7b0712ec1a7843b6d2e339af9ee8538b5c8c49e80' 
  AND token = 'CFtBa66CKpGYpPeM2eXeNGN4+Osc3e6nxwK7Tx0AV2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}