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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1219366a1d6beee7328a6ec3e770574ca4662fcf4b752ca3cab228750736823f' 
  AND token = 'Vat8iB93vRQE848id9Uk2OYsIdTtn1Rrnt8L3Z/xp84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}