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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b285135db1fb205b1fe0744549f2448dbe52e3eb654273e0ace7752ce52a194' 
  AND token = 'mQsSn2fn7O6LoxHxUbQ9DWa+X7w1+md3fwapAAN4u9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}