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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6777c66abc81f2d1e5327d38a4933b39017d0495b9cfcc667a57f51706d11dcc' 
  AND token = 'ppVL60PSgL6S0MMh0dloDKGveyiID/hNKQL/dgmnT7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}