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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c5b02f985963e56d3f281fbc0f99a1468b3fd6c6ab05b2f083afa059de12c41' 
  AND token = 'jYTVvM+cw6jXo2XXdnNb4JzRw0hDqsaxdpCA/kvksJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}