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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16b7499556a90210a8b4c11a27c015ca26166b8c6466f1142ee86c704f2c3896' 
  AND token = '3K2CnYM+B3glkCzJlj7bMogYA2COPprhBRifxslP000=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}