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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74e434d8f163e8d2050471f8e25930f2ffe98a2a130dea027f9f08550853ff18' 
  AND token = 'hPKKevXZXO2XZ41xH6ttifIg+KPBBA4ZvyPrJpPmTVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}