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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e806cd06005d4b05c3da5a46fced46959680c85b15eceebcaf209ed88a8dfe3' 
  AND token = 'ES84fLEbcKWC4a4nn80rPcoOggq1ZyUxxOLpAdX2ndg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}