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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d6e373fdd4f53169d468b97c38532e2ae06a6f4b0bc131533cb825beec5e04b' 
  AND token = 'QBTwscC+1e6n1XCxR9Rfd/T+UoWeJGaHJqyyU9HOY9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}