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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '164e260063d6a2c626fb0d41d37e98adc9ad53af03c6f0c45cef559110fbf32c' 
  AND token = 'aEQA/k4rA71CWYahN/Z8SoJSOzUH2OBbrmQzRiNZWvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}