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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5c8f5514d6260c537ab7e40c29d363e85d0af0851f867bdbe0f25bc939b6889' 
  AND token = 'IeOpbfWd6E4JXjVBK7zzayOX4JjLsfWJdUvxxsC5rSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}