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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e50526af84353ae59a62ff6f26060354d9d183e8e4c179575927f9151f4dc604' 
  AND token = 'ox0APvymO8O2upHEkxqEyWbm/Th74Tkg3lH2+Izie9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}