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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fb8c8c035bce06406e1c335b1b748e119fbc8543bbf5ec7a2667a44f8f885d7' 
  AND token = 'm8CbIfE64XvOwk5ZK13w0XlcAfMO79ODRJN8CNB7S58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}