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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '757ea8e39eff092b241d8b9d0b500f820efe55145b1847c8fd26e4e8c070277c' 
  AND token = 'bADd7Qg++caqinaQuNyDQYtjxUnslw4aZk/OAOWFH68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}