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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b00f16adf8e9e416689dfeddd31050ccf1eb6a5cd69394423b2754738d8a1c5f' 
  AND token = 'trHXT59UfIwCM4w4Z76RuLldXWw4nFifULNfWx4/aqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}