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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c75c5d070f1de3d3e82ee4bf4be12f459210e85409d3d2fff71b8530429e4058' 
  AND token = 'v5oIj9I3SxTsrFtlg8ZFlKo1RuotvD1KNpNoiBbgXjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}