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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8815585e1c0fe495fe80d4a02986e15882d52134adf7b27b3fe3cfea24798516' 
  AND token = 'XovrvOL1Cc79vNzBSbnWCYVIu+uTuP1amjjisBV2E4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}