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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25127579a6f7c4b8abfb072bc44bcfb5faeacf1ef89efac0accade9bb2d90f19' 
  AND token = 'wRCkL5iXLbjWNWdd/lrKoUhn01GHEHKbkU6rr7EVazI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}