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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d14b340bd1725e6239db2b2f08c66c3c2da7b5a60944519f99c3be2a09c4737' 
  AND token = 'XxnbKwlYlqr3nsaKqRYQueI/7vtDaOURmTcqXO02DMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}