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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73bd12b048aad121a053a70de61b642e07a0c6234063d084fd38bf21b24b0d14' 
  AND token = 'cxCDxg3VgbmERY0qZQCSGoeN4NqqHG0ZxLHdLwOTWvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}