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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0b4b96735c67435c1e1762de883a8d5b19bb8b9fe485ee44e88d1f75f245000' 
  AND token = 'BJ+NWQdgMqaUAE3goct1kE4TnqWKbUQHtHEPdPYrK0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}