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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0e750475a361a59326b6b620fcf70e12a8179ba7403b2d0a47e53b76e26159e' 
  AND token = 'gj+1QcQkLLfUq7bD3FRwK6gYa2pa5NxwEcaX5Z54rb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}