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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41ecfed0cd9d0d6067aa24727d601fd3471d4dc977ddbda0b246ec360d03d24d' 
  AND token = '3ZcADh3Dbg19v1lryKB6P6RTQgQ6jEVq5GrjzhAekok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}