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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6570ddb4372cc27c2fb767a6cf528a4d152f24fb38828fdb49dc94a1dbbca5a8' 
  AND token = 'bU9rN8lB+yAFQuuuOD5tKLvGJzkN2EEExy0fjXOVMqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}