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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2082a5375a2beca6344354b006e1c68157e07b29deb15cc7d698dc044c68b209' 
  AND token = 'BB066K/FtzxCKl9jfDvIjg3ssbRUWm3IfA2rqdtdgJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}