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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f185ee2e29a577e6612e8941801a75260ff627646f4f7ec5643e53d0d779a477' 
  AND token = 't/XwWPQyErpgj2VE9iGZd3V+ycywFohC4QOtynHD/4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}