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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '048978f4a2b21f4c25291ec67f83a9e11fb41f2c5ca190c0d25b6e88617dcfcc' 
  AND token = 'OzBL4er/WXA2qpppidAY+apOb3w3/1I1dPEAiLu8sRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}