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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a9015e4e79b44ee8c1eedef0932bc2acaad65ecda472ec126ed89344e090074' 
  AND token = 'vUmM9dNvVHWBohImplTO+xEsCBP8Vk+E8HR8eFYYkBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}