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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fb414a1e14498fdcf494edbba0d2890a38e1490a71d46bb3646a50973c0a4c8' 
  AND token = 'QW7m3kNnB42eTmGJCq3CihXvHwHjFZleyZKhnVMncqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}