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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f67e22cea96b50b7cd327458c6cf3c0296b80b6a0c6e53b4eec4b9832e2da85' 
  AND token = 'akMo4sC4fcO08RNrOlW8fYrUnNC5LVEQN8UDsp2HVQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}