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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa2b7d343fe78678dc92e0b7216a17eb417b332d62b6b016e4227256095e5d16' 
  AND token = 'KHHAH32gizs7jXGLtq/+tceGaz9eIylnVlAPGwV6eh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}