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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b47f243946eca361ebfb74ae29e3845f8ca9c4aa4fda334e39ba15398f4464e4' 
  AND token = '33vnkAfQtY6c/sZoSbQ2l6i04F1sVRdOZZ8hh8Z4KQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}