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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '867f52e86401ab80c7b82146e003708d727a1f6bfa49fdfe37fc13d6b5e03bbd' 
  AND token = 'kViflOVFV7nNEOYy6vp5WmGJAH3EXoIAjrR6wv+AHyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}