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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '330738738def6ac2571ce58f1e7c680c637925c646fb3bf82f717f2e9d761fe0' 
  AND token = '4ZhLXfjuGrX2rBw61sNjS8Rxdb6XtCVbKuIe62Z1uh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}